產品櫥窗
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Olaparib, >98%
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產品型號：101-763113-22-0 商品規格： |
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Olaparib is a potent inhibitor of both PARP-1 and PARP-2 and is strongly sensitive to KB2P cells due to suppression of base excision repair by PARP inhib
C24H23FN4O3
M.W.: 434.5
Olaparib is a potent inhibitor of both PARP-1 and PARP-2, with IC50 = 5 nM and 1 nM, respectively. Olaparib is strongly sensitive to KB2P cells due to suppression of base excision repair by PARP inhibition, which may result in the conversion of single-strand breaks to double-strand breaks during DNA replication, thus Olaparib has an effect on activating BRCA2-dependent recombination pathways. Olaparib has been shown to induce significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo.
M.W.: 434.5
Olaparib is a potent inhibitor of both PARP-1 and PARP-2, with IC50 = 5 nM and 1 nM, respectively. Olaparib is strongly sensitive to KB2P cells due to suppression of base excision repair by PARP inhibition, which may result in the conversion of single-strand breaks to double-strand breaks during DNA replication, thus Olaparib has an effect on activating BRCA2-dependent recombination pathways. Olaparib has been shown to induce significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo.
Store at -20℃