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  • Colistin Sulphate
  • 產品型號:101-1264-72-8

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Synonyms: Polymyxin E. sulfate; Belcomycine; Colomycin

C52H98N16O13·H2O4S
MW: 1253.51
Potency: >19000 U/mg

Colistin is a cyclic polypeptide antibiotic of the polymyxin family. It targets the cell membrane of bacteria, which ultimately leads to an altered cell permeability and cell death. It primarily targets gram-negative bacteria. Colistin has been used to study mannose-resistant haemagglutination, antibiotic resistance, and nephrotoxicity.

Stock conc.: 10mg/mL in 1x PBS. Use immediately.

Working Conc.:
Escherichia coli: 0.12–128 μg/mL
Klebsiella pneumoniae: 0.25–128 μg/mL
Pseudomonas aeruginosa: ≤0.06–16 μg/mL

Suzuki, T., Inouye, H., Fujikawa, K., et al. Studies on the chemical structure of colistin. I. Fractionation, molecular weight determination, amino acid and fatty acid composition. J. Biochem. 54(1), 25-33 (1963).
Store at 4oC