C23H26N5NaO7S
MW: 539.54
Purity: >87%

Piperacillin is an extended-spectrum β-lactam antibiotic resistant to many β-lactamases. It is derived from ampicillin and targets gram-negative and gram-positive bacteria. Additionally, piperacillin has been used in studies on optimization of antimicrobial therapy in patients with sepsis and to study piperacillin allergic reactions. It has also been used to study multidrug resistant organisms.

Piperacillin inhibits the last stage of bacterial cell wall synthesis by binding to certain penicillin-binding proteins (PBPs), which results in cell lysis. Cell lysis is mediated by bacterial cell wall autolytic enzymes. Piperacillin may interfere with autolysin inhibitors.

Solubility: 10mg/mL, in DMSO.

Stock conc.: 3mg/mL, in 1x PBS. Use immediately.