H2NCOCH2NHCH2CH2SO3H (C4H10N2O4S)
M.W. 182.20
Appearance: White solid
Purity: 98.0%-101.0%
pKa(25℃): 6.58-6.98
Abs.280nm(5%, H2O): 0.02
Solubility in water: 50mg/ml, clear, colorless

ACES is one of Good's buffers developed in the 1960s to provide buffers with pH ranging from 6.15-8.35 for use in various applications. It is often used as a buffering agent in biological and biochemical research,like, as a zwitterionic buffer with a useful buffering range of 6.1-7.5. There are many other published applications of ACES, such as be used to develop buffers for both agarose and polyacrylamide gel electrophoresis, used in isoelectric focusing of proteins, used in analysis of bacterial autolysins in a discontinuous SDS-PAGE system. Potential inhibition of ACES and other Good buffers has been investigated in γ-aminobutyric acid receptor binding to rat brain synaptic membranes.