C11H12Cl2N2O5
M.W.: 323.13
Assay: 99% Max.
Chloride (Cl): 100ppm Max.
Loss on Drying: 0.50% Max.
Cell culture tested
A white to Grayish-white or Yellowish-white Crystalline Powder
BP2002

Chloramphenicol is a synthetic antibiotic, which was first isolated from strains of Streptomyces venezuelae. It has a broad spectrum of activity against Gram-positive and Gram-negative bacteria. Chloramphenicol inhibits bacterial protein synthesis by blocking the peptidyl transferase step (elongation inhibition). It binds to the 50S ribosomal subunit and prevents attachment of aminoacyl tRNA to the ribosome. This antibiotic is often used in molecular biology applications for bacterial selection (10-20 μg/ml). The mode of resistance is inactivation of chloramphenicol (acetylation) by chloramphenicol acetyltransferase (cate gene).

Stock Conc.: 10 or 34mg/mL in EtOH, Store at -20℃
Working Conc.: 20-170ug/mL