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  • Levofloxacin(Stock: Inquire)
  • 產品型號:101-100986-85-4

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Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic. Synonym:LEVOFLOXACIN, Levaquin, Quixin, Cravit

C18H20FN3O4
MW: 361.4


Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with  antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth.

Douglas N. Fish.; Andrew T. Chow. The Clinical Pharmacokinetics of Levofloxacin. Clinical Pharmacokinetics. 1997, 32 (2),101-119 .
Richard Frothingham M.D. Rates of Torsades de Pointes Associated with Ciprofloxacin, Ofloxacin, Levofloxacin, Gatifloxacin, and Moxifloxacin. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 2001, 21 (12),1468-1472 .
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