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  • Mitomycin C
  • 產品型號:101-50-07-7

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Selection Antibiotics.

C15H18N4O5
M.W.: 334.33
Assay: 970ug/mg Min.
Water: 2.5% Max.

Inhibitor of DNA synthesis, nuclear division, and cancer cells. Antibacterial to gram positive, gram negative, acid-fast bacilli.

Stock conc.: 0.5 mg/mL in ddH2O (pH6.0-7.5), protect from light, store at 4℃. 
Use the stock solution in one week. Working conc.: 10–50 µg/mL for eukaryote cell culture.

Tomasz, M., Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA. Science 235, 1204, (1987)
Ueda, M., Sequence-specific DNA damage induced by reduced mitomycin C and 7-N-(p-hydroxyphenyl)mitomycin C. Nucleic Acids Res. 12, 6673, (1984)
Y. Hashimoto et al. Acc. Chem. Res. 17, 403, (1984) 

 

Store at 4℃, protect from light 

very toxic