MW：164.16

p-Coumaric acid has been used as a component of chemiluminescent substrate for protein detection in western blotting.

p-Coumaric acid is mainly a plant metabolite which exhibits antioxidant and anti-inflammatory properties. It also shows bactericidal activity by damaging bacterial cell membrane and by interacting with bacterial DNA. In western blot, p-coumaric is also used as an enhancer in chemiluminescent substrate.

Hydroxycinnamic acid found in many fruits and vegetables.

Olga I. Tarzi.; Hiroshi Nonami.; Rosa Erra-Balsells. The effect of temperature on the stability of compounds used as UV-MALDI-MS matrix: 2,5-dihydroxybenzoic acid, 2,4,6-trihydroxyacetophenone, α-cyano-4-hydroxycinnamic acid, 3,5-dimethoxy-4-hydroxycinnamic acid, nor-harmane and harmane. Journal of Mass Spectrometry. 2009, 44, (2), 260-277.

Jeong-Yong Cho.; Jae-Hak Moon.; Ki-Young Seong.; Keun-Hyung Park. Antimicrobial Activity of 4-Hydroxybenzoic Acid and trans 4-Hydroxycinnamic Acid Isolated and Identified from Rice Hull. Bioscience, Biotechnology, and Biochemistry. 1998, 62, (11), 2273-2276.