產品櫥窗
-
Hemin, >98%
|
產品型號：101-16009-13-5 商品規格： |
 |
Hemin is used in cellular protection and control mechanism. Synonyms: Hemin chloride Chloro(protoporphyrinato)iron(III)
C34H32ClFeN4O4
M.W.: 651.94
Hemin, the oxidized version of heme, is an iron-containing prosthetic group for a diverse group of proteins. Free heme, which can be released from hemoglobin following hemolysis, is pro-inflammatory and contributes to iron-derived reactive oxygen species. Free hemin levels may be upregulated in various pathological conditions and can contribute to various inflammatory conditions including vascular disorders, renal failure, and immune-mediated disorders.
Hemin may be used to study the expression and represson of heme oxygenase 1 (HO-1) as well as the activity of HO-1. Hematin is the "X factor" required to grown Haemophilus influenzae.
Application:
Hemin is used for the following applications:
• To study bacterial strains and growth conditions.
• Used in short-term colony assays (the culture medium consists of hemin along with other components).
• Cell transfections.
It may be used in β-hematin formation assay for analyzing the inhibitory activity of MMV (Medicines for Malaria Venture) Malaria Box compounds against the formation of β-hematin.
Sophie Joly et. al. Journal of clinical microbiology, 42(3), undefined (2004-3-9)
S Abboud and D J Haile. The Journal of biological chemistry, 275(26), undefined (2000-4-5)
A Curti et. al. Journal of immunology (Baltimore, Md. : 1950), 166(2), undefined (2001-1-6)
Kim Y Fong et. al. International journal for parasitology. Drugs and drug resistance, 5(3), undefined (2015-7-8)
M.W.: 651.94
Hemin, the oxidized version of heme, is an iron-containing prosthetic group for a diverse group of proteins. Free heme, which can be released from hemoglobin following hemolysis, is pro-inflammatory and contributes to iron-derived reactive oxygen species. Free hemin levels may be upregulated in various pathological conditions and can contribute to various inflammatory conditions including vascular disorders, renal failure, and immune-mediated disorders.
Hemin may be used to study the expression and represson of heme oxygenase 1 (HO-1) as well as the activity of HO-1. Hematin is the "X factor" required to grown Haemophilus influenzae.
Application:
Hemin is used for the following applications:
• To study bacterial strains and growth conditions.
• Used in short-term colony assays (the culture medium consists of hemin along with other components).
• Cell transfections.
It may be used in β-hematin formation assay for analyzing the inhibitory activity of MMV (Medicines for Malaria Venture) Malaria Box compounds against the formation of β-hematin.
Sophie Joly et. al. Journal of clinical microbiology, 42(3), undefined (2004-3-9)
S Abboud and D J Haile. The Journal of biological chemistry, 275(26), undefined (2000-4-5)
A Curti et. al. Journal of immunology (Baltimore, Md. : 1950), 166(2), undefined (2001-1-6)
Kim Y Fong et. al. International journal for parasitology. Drugs and drug resistance, 5(3), undefined (2015-7-8)
Store at 4℃